Autism spectrum disorder (ASD) is characterized by a complex interplay of neurological and behavioral differences, resulting in a broad spectrum of symptoms and challenges. This course explores the various aspects of autism, including its definition and diagnostic criteria, medical assessments, treatment interventions, and support systems available for individuals and families affected by the disorder. This course will also highlight the conditions that can mimic or be mistaken for autism, explain the importance of personalized care and support, and discuss nursing considerations when caring for patients with autism, emphasizing the importance of holistic and person-centered care in addressing the diverse needs of individuals on the autism spectrum.